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In addition, the indole Main is substituted at R3 with a carbonyl team which is also bonded to some napthalene moeity. Napthalene is a bicyclic composition of two fused benzene rings. This carbonyl bridge of JWH-018 classifies it being a ketone. JWH-018 is undoubtedly an analog of THJ-018, during which the Main indazole construction is substituted